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And so this hypotension also affects the health of blood vessels of the heart. Chen said it is important for researchers to continue to find new ways of protecting kidney function in people who are obese with heart disease because kidney disease has significant morbidity and mortality in the So any treatments we have to slow the progression of kidney disease have the potential to benefit a large portion of the American population, he continued

The clearest answer to date comes from a Phase 2 trial published in the New England Journal of Medicine in 2023, which reported 24.2% weight loss after 48 weeks at the highest dose in 338 adults with obesity but no other complications

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Long-term follow-up of childhood cancer survivors who later received GH likewise showed no significant rise in relapse or secondary malignancy rates