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When to contact your GP: Before starting any weight loss medication If you experience concerning side effects from current medications If you have not achieved meaningful weight loss (5%) after 12 weeks of treatment If you are considering combining medications or supplements If you have symptoms suggesting complications (chest pain, severe abdominal pain, persistent vomiting) Report any suspected side effects to the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)

No, this isnt necessary as you cannot overdose on vitamin b12, the body will store what it needs and get rid of the rest

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Professor Jastreboffs research contributions include: Principal investigator for GLP3 phase 2 obesity trial demonstrating 24.2% weight loss Leadership in clinical research examining triple hormone receptor agonists Extensive investigations of incretin-based therapies for obesity and metabolic disease Pioneering work on combination approaches to weight management Studies examining neurobiological mechanisms underlying obesity pharmacotherapy Her work has helped establish GLP3 as one of the most promising next-generation obesity treatments in clinical development, contributing to the scientific foundation for multi-pathway metabolic interventions