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A 2023 study by the International Islamic University of Malaysia put the figure at RM234 million in lost productivity, or around RM12,000 a patient

[38] Although initial reports suggested mildronate is a non-competitive and non-hydroxylatable analogue of gamma-butyrobetaine, [39] further studies have identified mildronate is indeed a substrate for gamma-butyrobetaine dioxygenase

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