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Ueland T, Svardal A, Oie E, Askevold ET, Nymoen SH, Bjorndal B, et al
This is why the recommendation for T/T individuals is specifically active folate rather than folic acid folic acid accumulates as unmetabolized folic acid in the circulation of T/T individuals, potentially with pro-inflammatory consequences, rather than supplementing the genuinely deficient 5-MTHF pool
A P value of less than 0.05 was considered statistically significant for univariate/1-group analyses