3.4.2 RF induces ferroptosis: a vicious cycle RF and ferroptosis form a self-perpetuating loop: 1) RF-driven CKD progression reduces renal function, causing hematuria, renal anemia, and increased tubular iron filtration/exogenous iron intake, leading to iron overload and ferroptosis
This disruption can lead to gastrointestinal upset, including increased bowel movements or loose stools, commonly known as diarrhea
Smoking reduces blood flow to organs and raises harmful molecules that damage the liver
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