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So, with little previous research in this area we were keen to understand why this was the case and to find out what impact there was on the safety of patients. She added: We believe there is an opportunity for healthcare professionals to encourage patients to come to them for advice as our research showed that 72% are finding information around medication from online, closed support groups

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The most frequent symptoms are: Developmental delays Anaemia Loss of appetite Chronic vomiting Weight loss Low brain volume Spasms/cramps Apathy Irritability In the most severe instance, vitamin B12 deficiency can lead to respiratory failures and coma (51)

Dysgeusia can also affect appetite and nutrition