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Two new peptide medications have been released which use one or both of these mechanisms of action

Tesofensine is a triple monoamine reuptake inhibitor that increases metabolic rate by 1015% and reduces hedonic eating drive by blocking reuptake of dopamine, norepinephrine, and serotonin centrally in the brain

For individuals who struggle with the side effects of oral metformin, an alternative exists: Oana Health's Metformin HCL Lotion 20%, available for $43 per month, significantly reduces gastrointestinal discomfort

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Watching for symptoms, checking blood pressure, and managing other medicines can reduce the risk