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These findings support morin hydrates potential as an adjuvant therapy to mitigate cisplatin-induced toxicity (170)

5 Progress in research on clinical intervention strategies Table 2 summarizes key intervention strategies and their mechanisms, helping to provide a clearer understanding of how each strategy targets ferroptosis and its potential application in cardiovascular diseases and other related conditions (12, 37)

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G6PDH-generated NADPH regulates oxidative protein folding Given that GSEA suggests a progressive, differentiation-related malfunctioning in G6pdh chon growth plates, we first focused on understanding the link between NADPH-mediated GSSG recycling and protein processing in ER, as this pathway was most increased in the resting chondrocytes (Extended Data Fig