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However, headache incidence rates were similar between AOD-9604 and placebo groups, suggesting that many cases represented background occurrence rather than treatment-related effects

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While the metabolic benefits of GLP-1 medicines, such as improved glucose control and weight loss, improve health and likely help reduce metabolic diseaseassociated complications, a growing body of evidence suggests that GLP-1 has intrinsic antiinflammatory actions that are independent of its metabolic actions