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Conversely, patients with IBS-C (constipation-predominant) may experience worsening symptoms when using these medications

[5] Despite seemingly significant risk of side effects and lack of adherence to a drug regime, the prediction is that the market will continue to grow by 18% year over year

Because those with this mutation are already at higher risk of mental disorders, this is an important preventative measure

However, the application of estrogen also presents several side effects, such as stimulation of the gastrointestinal tract, an increased risk of thrombosis, and the potential risks of breast cancer, endometrial cancer, and venous thrombosis (Zhao et al., 2025)

4, July 2019, pp