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A Japanese open-label trial, with dapagliflozin, showed positive effects regarding steatosis and fibrosis, measured with non-invasive techniques, through liver stiffness measurement (especially in patients with stiffness equal or greater than 8 kPa), 71 while similar results were reported from the double-blind EFFECT-II study (NCT02279407)

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Additionally, the trypanothione reductase gene is amplified in antimony-resistant isolates, leading to high intracellular trypanothione levels and increased resistance to SbIII ( Sequestration and rapid drug efflux also contribute to antimony resistance

10.1210/endo-119-4-1467 60 ParizadR.BattaA.HatwalJ.Taban-SadeghiM.MohanB

Funding This study was funded by the National Natural Science Foundation of China (Nos