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Because of its potential to enhance metabolic efficiency and endurance, MOTS-c is on the WADA Prohibited List in category S4

U.S.-born Black and Hispanic individuals exhibit similar microbial patterns at the s-OTU level

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In contrast, treatment with [Nle 4 ,D-Phe 7 ]--MSH does not result in a significant increase in cointernalization when compared to controls (Schellekens et al., 2013)