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This level of weight loss is significant not only for cosmetic reasons but also for its potential impact on overall health

Furthermore, elevated ROS levels can damage DNA, leading to oxidative DNA damage

Thus, by its enzymatic detoxification of nonradical hydroperoxides, GPx-1 regulates cellular oxidant status directly through elimination of hydroperoxides and via oxidation of GSH, the major low-molecular-weight thiol in cells

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It is unknown whether WEGOVY causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined [see Warnings and Precautions (5.1), Nonclinical Toxicology (13.1)]