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It contains two long-acting peptide analogues: cagrilintide, a synthetic amylin receptor agonist, and semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist

With each session, we steadily wear away at the tattoo, resulting in progressive fading

Triple agonists add glucagon receptor activation, which: Increases resting energy expenditure by 8% to 12% (Jall et al., Diabetes Care 2024) Promotes hepatic fat oxidation and reduces steatosis May offset some of the lean mass loss seen with GLP-1 monotherapy (early signal, not yet confirmed in long-term trials) The weight loss ceiling for retatrutide appears to be 24% to 26% based on phase 3 data, though long-term real-world outcomes are not yet available

However, focusing only on the scale can be misleading

Though not exhaustive, the paragraphs below summarise its main virtues and therapeutic applications