All authors contributed, reviewed and approved the final version of the manuscript
doi: 10.1136/bcr-2021-246432 Pubmed Abstract CrossRef Google Scholar 55 Di FilippoLCastellinoLGiustinaA
For example, a large Finnish study found that drinking more than one serving of alcohol per day can decrease sleep quality for women by nearly 40 percent
68,69 Investigators have noted lower GSH concentrations to be associated with the combination of advanced age and increased risk of chronic diseases such as chronic renal failure, malignant disorders, diabetes, alcoholism, Parkinson's disease, and cataract formation
The main reasons for this drop include increased activity of NAD+-consuming enzymes like PARP1 and CD38, triggered by inflammation or DNA damage