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Inhibitors of FSP1 and inhibition of ACSL4 (e.g., through a high-fat diet) can increase and decrease the sensitivity of cancer cells to ferroptosis, respectively [241, 242]

Since naturally occurring inhibitors of melanogenesis usually garner more attention compared with chemically synthesized compounds due to the cosmetic demands of consumers, the present review focuses on natural compounds that have been documented to exhibit skin-whitening effects through the inhibition of TYR activity

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