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In some experiments cells were pretreated with the JNK inhibitor V (Calbiochem, Merck KGaA, Darmstadt, Germany)

The loss of redox homeostatic balance in the brain in the presence of increased ROS or reduced GSH and similar antioxidant molecules may suggest a pro-inflammatory aetiology in MDD

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Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease - novel insights into cellular communication circuits