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The greatest benefit was observed among patients who were nave to DPP-4 inhibitors, but a significant reduction in HbA1c was noted even after switching from a DPP-4 inhibitor to oral semaglutide

Cosmos Study November 13, 2025 Dual-Team Study Team A:Kersten Bartelt, RNDan GreerEmily Higgs Team B:Louis Kazaglis, MDTed Stamp Key Findings Among patients with polycystic ovary syndrome (PCOS), the median one-year weight change was an 11.5% loss for those treated with a GLP-1, compared to a 1.9% loss among those treated with metformin

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