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These may be indirect effects related to dietary changes, altered eating schedules, gastrointestinal discomfort, or the psychological adjustments that accompany significant weight loss

Common Degradation Pathways Deamidation of asparagine residues Methionine oxidation Peptide backbone hydrolysis Acyl chain hydrolysis Isomerization reactions Advanced LC-MS methods allow researchers to identify the exact location of degradation events within the peptide sequence

You cannot start taking GLP-1 medications if you are pregnant, trying to conceive, or nursing

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doi: 10.1016/j.dci.2020.103666 98