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The estimated treatment ratios of the mean AUC 0 of cagrilintide in each of the renal impairment groups to the normal renal function group were 1.23 (90% CI, 0.911.66) for the mild renal impairment group, 1.18 (90% CI, 0.871.59) for the moderate renal impairment group and 1.21 (90% CI, 0.871.68) for the severe renal impairment group
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Some alternatives may have different potency, stability, or side effect profiles
Anyone with personal cancer history, family history of hormone-sensitive cancers, or current suspicious masses should avoid GH secretagogues and IGF-1 elevating protocols
PMID 11713213
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