Used as biochemical reagents, detoxification drugs, it is mainly used for the poisoning of heavy metals, acrylonitrile, fluoride, carbon monoxide and organic solvents
Because MPTP is a lipophilic compound, it can cross the BBB, and be taken up by astrocytes where it is converted to MPP+
Even mild dehydration can knock your immune system down by 30% and leave you feeling foggy and tired
A recent systematic review comparing 10 different GLP-1RAs as an add-on to metformin highlighted key variations in their efficacy and safety
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