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Cotadutide, a glucagon-like protein-1 receptor (GLP-1R) and glucagon receptor (GCGR) agonist, was shown to reduce blood glycaemia, body weight and hepatic steatosis in people with type 2 diabetes mellitus

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Abbreviations Ctrl: Control EASE: Expression analysis systematic explorer FDR: False discovery rate GSH: Glutathione GSSG: Glutathione disulfide KO: Knockout MAPK: Mitogen-activated protein kinase MT: Metallothionein PCA: Principal component analysis PHH: Primary human hepatocytes RLU: Relative light units ROS: Reactive oxygen species WD: Wilsons disease References Sandahl TD, Laursen TL, Munk DE, Vilstrup H, Weiss KH, Ott P (2020) The prevalence of wilsons disease: an update

Paris, M.D., (Mauclair-Dacier), vers 1900

Pharmacological Approach in Patients with PWS Besides nutritional management, GH replacement therapy in PWS children with GHD has demonstrated to decrease FM, increase FFM, and improve both motor and mental performance [92]