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Defects in components of the sex determination pathway result in mutants that fail to differentiate into mature gametes appropriately 18,19

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The growth hormone (GH)-axis of GH receptor/binding protein gene-disrupted and metallothionein-human GH-releasing hormone transgenic mice: hypothalamic neuropeptide and pituitary receptor expression in the absence and presence of GH feedback

The apoptosis level was detected using Click-iT TUNEL Alexa Fluor Imaging Assays Kit (C10246, Invitrogen)