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Vitamin D also plays a neuroprotective role, with its receptors spread throughout brain tissue

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Extracellular vesicles released during normothermic machine perfusion are associated with human donor kidney characteristics

Activation of the nuclear factor erythroid 2related factor 2 (Nrf2) pathway directly raises GSH levels, upregulates the transcription of genes involved in antioxidant defense, provides mitochondrial protection, facilitates the proliferation of detoxification enzymes and modulates neuroinflammation (Guerrero-Beltrn et al., 2012