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Wachter S, Vogt M, et al

The multi-peptide formulation may produce additive effects, most commonly during initial dosing phases

Some combinations work synergistically, enhancing overall effectiveness, whilst others may compete for absorption or provide redundant benefits

Thus, integration of both hormones into a single molecule may not only maximize the metabolic efficacy of the individual signals, but allow also specific delivery of estrogen into GLP1 receptor-expressing cells, avoiding potential undesired effects of estrogen on reproductive tissues, as shown also in our studies