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2.4.1.2 Determination of Sample Size Based on 21 subjects completing the trial, Trial 1 was calculated to have an overall combined statistical power of at least 80% of concluding no effect for the four endpoints (i.e

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[4] U pacjentw z otyoci i jednoczesn cukrzyc typu 2, czyli w badaniu SURMOUNT-2 , efekty byy nieco mniejsze, ale nadal klinicznie bardzo istotne: rednio 12,8% dla 10 mg i 14,7% dla 15 mg po 72 tygodniach, versus 3,2% w grupie placebo