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Wegovy is not intended to be used in combination with other GLP-1 RAs or weight-loss medications, as this could lead to an increased risk of adverse effects

Improved gastrointestinal tolerance is the primary signal that dose escalation is safe

While medications like Semaglutide exclusively target GLP-1 receptors, Tirzepatide simultaneously stimulates two critical hormone pathways: the GLP-1 receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor

This dual action affects two metabolic pathways, which can lead to broader improvements in blood sugar control and additional benefits in weight management

Demand for injections that use the active ingredient sold under the brand names Ozempic, Wegovy and Rybelsus has rocketed after it was hailed as a game changer for fighting obesity