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In addition to being neutrophilic, pyocyanin has been shown to accelerate neutrophil apoptosis (107110)

In fact, there are more than 600 different types of carotenoids found in nature, but only about 20 make their way into the eyes

Available online: 64.Rohrer J., Lupo N., Bernkop-Schnrch A

This proposed concept mirrors forward genetics, we know the external phenotype is melanoma, therefore doing a high throughput un-biased screen for serum biomarkers will reveal expression changes of biomarkers between healthy controls, disease-free patients, and melanoma patients, which will provide insights into key driver pathways regulating metastasis