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These include: Personal or family history of medullary thyroid cancer or multiple endocrine neoplasias Personal or family history of parathyroid cancer or pancreatic cancer Being pregnant, trying to get pregnant, or breastfeeding History of anorexia, bulimia, or body dysmorphic disorder Type 1 diabetes Diabetic retinopathy Renal insufficiency Vitamin B12 allergy History of pancreatitis or pancreatic disease History of gallbladder disease ( NOTE : If your gallbladder has been removed, you can be considered for semaglutide use) Common Side-Effects As with any medication, there are some common potential side effects from semaglutide use

However, there are some downsides to consider

Tricyclic antidepressants (TCAs)

Laboratories frequently apply synthetic modifications to these molecules

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