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Mice were divided into five groups: (1) chow diet group [(CD), 3.85 kcal/g dry wt, 19.2 g/100 g protein, 67.3 g/100 g carbohydrate, and 4.3 g/100 g saturated fat]

This effect appears related to the peptides effects on connective tissue and fluid retention

However, if you lose a substantial amount of weight quickly - whether through bariatric surgery, diet and exercise, or weight loss medications like Ozempic - you may lose fat faster than your skin can bounce back

Moreover, IL-1 inhibits L-type calcium channels, impairing cardiomyocyte contractility and exacerbating heart failure progression

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