It is notable that even if the pathway is absent, ascorbate is present in some of these compartments, albeit in more oxidised form (Conklin et al
Deficiency in vitamin B12 may cause anemia, fatigue, muscle weakness, intestinal problems, nerve damage, and mood disturbances
Evidence Quality Summary The honest assessment: mechanistic data is compelling, animal data is supportive, and human data exists but is not conclusive for GHK-Cu alone
Because of this role, vitamin B12 is critical for producing and maintaining hair follicles and healthy hair growth
Some patients may require an even higher dose of 2 mg weekly for optimal effect, particularly for weight management indications, though this should be approached cautiously with careful monitoring for adverse effects