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Regarding the mechanism by which GLP-1RAs are taken up into the brain, it has been reported that GLP-1RAs do not cross the blood-brain barrier through endothelial cells [5]

Advanced Digestive Enzyme Complex with 14 Enzymes: GLP1 supplement with a comprehensive blend of digestive enzymes such as amylase, protease, and lactase to support protein, carbohydrate, and fat digestion and help maintain digestive comfort

GLP-1 works by signaling the brain that the body is full, even with smaller portions of food, and by slowing the emptying of the stomach

The injectable safety profile is unknown

And I think the research backs it up