GLP-1 is a 30 amino acid-long peptide hormone mainly produced in the intestinal L-cells of the gut that is secreted into the blood ( Figure 1 ) (Habib et al., 2013

JAMA suggests avoiding lying down for 2 to 3 hours after meals if heartburn is an issue) Symptom-based food swaps If you feel nauseated Try: Dry toast, oatmeal, broth-based soup, ginger tea, a small protein portion Instead of: Fried foods, heavy creamy meals, large portions If you have heartburn or reflux Try: Smaller meals, baked or steamed foods, stay upright for 23 hours after eating Instead of: Late-night big meals, greasy foods If youre constipated Try: Add fiber slowly (oats, apples, beans) plus extra water Instead of: All protein, no plants days or very low fluid intake If you have diarrhea Try: Bland foods, fluids, simpler meals, talk to a clinician if it persists Instead of: High-fat meals, large sugar loads If your appetite is very low Try: Protein shake, yogurt, soup, smaller meals plus snacks Instead of: Skipping meals all day A simple 1-day sample menu This is not the only right plan. It is a template built for GLP-1 realities: lower appetite, smaller portions, protein first

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Abstract There is growing interest in the relationship between Alzheimers disease (AD) and diabetes mellitus (DM), and the glucagon-like peptide-1 receptor (GLP-1R) may be an important link between these two diseases