Patent protection: Another reason for the high cost of GLP-1 drugs is the active patent protection granted by the government
Furthermore, unlike long-acting GLP-1 analogs that also signal through the incretin pathway, DPP-4 inhibitors do not require parenteral administration, and their long-term use is associated with a low risk of gastrointestinal adverse effects and no meaningful increases in heart rate [37,38,39,40]
Drinking enough fluids, staying active and eating fibre-containing foods may help
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Following reconstitution, solutions require immediate refrigeration between 2C to 8C to maintain structural stability throughout the duration of the experimental protocol