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Finally, the efficacy of these next-generation balanced ( 16 ) and imbalanced ( 19 ) triagonists for weight reduction, food intake, and glucose control was further benchmarked against the published first generation triagonist [43] as well as the recently disclosed, balanced triagonist SAR441255 [51]

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Human studies echo these findings

Hypersensitivity Reactions Inform patients that serious hypersensitivity reactions have been reported during postmarketing use of BYETTA