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Mechanistically, because acylcarnitines are direct metabolites derived from fatty acid and organic acid catabolism, disruptions in systemic FAO under metabolic stress, such as during the introduction of enteral feeding in a compromised gut, could theoretically contribute to gut-specific toxicity

This meta-analysis encompasses the most recent and high-impact clinical trials, particularly those by Malhotra et al

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Both peptides are used off-label in the United States and require medical supervision