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GSS gene mutations can severely decrease glutathione levels, leading to a deficiency disease

10.1007/s00394-015-0922-1 Eur

Formula : CCHNNOS Synonym(s): N,N-[Dithiobis[1-[(carboxymethyl)carbamoyl]ethylene]]diglutamine-13C4,15N2 GSSG-13C4,15N2 Glutathione Disulphide-13C4,15N2 Glutathione Oxidized-13C4,15N2 Glutathione-S-S-glutathione-13C4,15N2 Glutathione-SSG-13C4,15N2 Glutathone Disulfide-13C4,15N2 Oxidized L-Glutathione-13C4,15N2 Oxiglutatione-13C4,15N2 CoA, MASS, NMR and HPLC will be provided along with the compounds

In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation

doi: 10.4110/in.2021.21.e3 236 SaadatM