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Small capillaries exist everywhere, and occasionally hitting one is unavoidable

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Establishing centralized databases, similar to the WHO-Adverse Drug Reaction (ADR) database, for reporting nutraceutical-related adverse events could significantly improve real-world risk monitoring

In many cases, starting with 250mcg per day is enough to stimulate healing without overstimulating pathways or triggering unwanted reactions

The overall heterogeneity for MACE was low (I 2 = 15.3%, 95% uncertainty intervals, 0 and 52.3%) (Table S3)