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For example, GLP-1s offer cardioprotective effects, likely mediated by improved endothelial function and reduced inflammation
however, YTHDF1 overexpression significantly increased LDH release (Fig
extended-release) which well talk more about below
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Trial participants experienced different levels of % total body weight loss depending on the dose: Percentage of total body weight loss on retatrutide After 48 weeks , 83% of patients taking 12 mg lost at least 15% of their body weight , compared to just 2% of those who were on a placebo
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