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(2) Improve patients' quality of life Cancer cachexia not only affects the physical condition of patients, but also has a negative impact on their psychological and social functioning

Kidney Impact: Similar to other NSAIDs, it can impair renal function, particularly in dehydrated patients or those with existing kidney problems

Phase 3 Development & Timeline Orforglipron's Phase 3 clinical development program is one of the most comprehensive in the history of obesity and diabetes pharmacotherapy, encompassing multiple trials across two parallel programs: the ATTAIN series for obesity indications and the ACHIEVE series for type 2 diabetes

206 This helps prevent the progression of NASH to liver fibrosis and cirrhosis