Notably, SCD endures overwhelming oxidative stress and consumes significant amounts of cysteine for glutathione (GSH) synthesis
GSH being regarded as the main cellular antioxidant that acts as determining factor of the cellular redox state by regulating various redox signaling by reacting with ROS that is produced in response to various stresses thereby acting as a major scavenger 50,51
Participation of phospholipase-A(2) and sphingomyelinase in the molecular pathways to eryptosis induced by oxidative stress in lead-exposed workers
Nn tham kho kin bc s hoc chuyn gia y t trc khi s dng, c bit l i vi ngi c tin s bnh l hoc ang s dng thuc khc
1182 Tofacitinib, a csDMARD, impairs glycolysis in RA-FLSs, decreasing the expression of HK2, GSK3A, LDHA, and HIF1A 1183 and promoting the dissociation of HK2 from the mitochondria