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Moreover, LC administrated for 2 weeks suppresses atrogin-1 messenger RNA (mRNA) level in suspended rats hindlimb [35], and only 7 days of LC administration downregulates MuRF-1 and atrogin-1 mRNAs reducing muscle wasting in a rat model of cancer cachexia [32]

L-Carnitine benefits for male athletes Men often use L-carnitine to support: Training endurance and recovery Fat metabolism during cutting phases Energy production during high-volume training Some research also explores its role in supporting sperm motility and reproductive health, though this is not its primary use in sports nutrition

And the answer has a bit of nuance

Post-hoc analysis of the power was performed with G*Power version 3.1.9.4

Their rise reflects more than just clinical efficacy: It highlights shifting attitudes toward obesity as a treatable medical condition, new capabilities in drug design and delivery, and unprecedented market momentum