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Some of these genes are up-regulated to act as sperm protective factors
A GLP-1R agonist (liraglutide) increased endothelial nitric oxide synthase phosphorylation and nitric oxide (NO) production by the 5-AMP-activated protein kinase (AMPK)-dependent pathway and subsequent NO production in cultured HCAEC [56],[57]
They also confirmed the lack of expression of GLP-1R in glial cells [4]
In ambito medico stato studiato per trattare alcune condizioni metaboliche, la stanchezza cronica, l'invecchiamento cellulare e le malattie neurodegenerative, anche se la sua efficacia pu variare a seconda del metodo di somministrazione e delle esigenze individuali
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