Under inflammation, the tryptophan catabolic enzyme, indoleamine 2,3-dioxygenase 1 (IDO1), is induced and that catalyzes the breakdown to Trp to N-formyl kynurenine, which is converted into a more stable metabolite, Kynurenine (KYN), and other downstream bioactive catabolites with profound immunomodulatory effects 49,50,51
The only differences are the indications each is approved for, not the medication itself
Mild stomach upset with oral capsules in some users
Burton GJ, Yung HW, Cindrova-Davies T, Charnock-Jones DS: Placental endoplasmic reticulum stress and oxidative stress in the pathophysiology of unexplained intrauterine growth restriction and early onset preeclampsia
Glia 65 , 15211534 (2017)