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With its multifaceted role, Se remains a cornerstone in the evolving landscape of thyroid disorder management

these ROS, including superoxide (O2), peroxide (H2O2 and ROOH), and free radicals (HO and RO), catalyze polyunsaturated fatty acid oxidation ( 2+ , hydrogen peroxide creates hydroxyl radicals (HO), which is the foundation of free radical lipid peroxidation, known as the Fenton reaction

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Both converge on the pituitary somatotroph but through distinct intracellular mechanisms