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While psoriasis mainly affects the skin, it is more than just a skin problem

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L-citrulline is a ubiquitous amino acid in mammals [13], and in the kidneys, vascular endothelium, and other tissues can be readily converted to L-arginine thus raising plasma and tissue levels of L-arginine which increases NOS synthesis and subsequent NO production [14]

The linear growth of children treated with corticosteroids by any route should be monitored, and the potential growth effects of prolonged treatment should be weighed against clinical benefits obtained and the availability of other treatment alternatives

Kroemer, G., Galluzzi, L., Kepp, O