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However, skeletal muscle-specific carnitine palmitoyltransferase 2 (CPT2)-deficient mice accumulate large amounts of acylcarnitine in muscle and plasma and still preserve insulin sensitivity [75], highlighting the role of acylcarnitine only as an indicator of FAO rather than as a direct mediator of insulin resistance [76]

This makes it a highly valuable adjunct therapy for managing the unpredictable, systemic flare-ups associated with Mast Cell Activation Syndrome (MCAS) and generalized histamine intolerance

Solvent: water

[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Verhaar MC, Stroes E, Rabelink TJ