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Possible side effects may include feelings of nausea, episodes of vomiting, and instances of diarrhea, relatively common but usually diminish over time

The controlled release of therapeutic agents, including systemic toxicity by limiting exposure to non-target tissues, enhancing patient compliance through reduced dosing frequency, and improving therapeutic outcomes by maintaining drug concentrations within a therapeutic window over time

doi: 10.9758/cpn.23.1086

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Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity PNAS