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Effetti avversi gastrointestinali (GI) Negli studi di fase 3, sia la semaglutide orale che quella sottocutanea sono state associate a disturbi gastrointestinali, come nausea, vomito e diarrea, effetti ben noti di questa classe di farmaci

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Del Prato S, Kang J, Trautmann ME, Stewart J, Sorli CH, Derwahl M, et al

While GLP-1RAs showed significant reductions in BMI, body weight and WC compared to either metformin or placebo, the lack of consistency in fasting glucose and hormone levels suggested that the impact of the interventions might have varied significantly across the different patient groups

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