The Glutathione System: A New Drug Target in Neuroimmune Disorders. Molecular Neurobiology, vol
"We currently don't know the long-term effects of many of these peptides
Several laboratory studies have reported that UA has pro-inflammatory properties, including triggering the Akt/PRAS40 pathway, inducing IL-1 release, promoting ROS generation, and activating the toll-like receptor (TLR) 2/4 and NF-B signaling [48, 49]
The intestinal serotonergic alteration together with the increase of proinflammatory cytokines also generates chronic inflammation, resulting in decreased acid secretion, breakdown of the intestinal barrier, decreased expression of enzymes necessary to digest carbohydrates, and alteration of the intestinal adaptive immune system, leading to the appearance of food intolerances and bacterial overgrowth in the small intestine (129, 181, 182, 184187)
Our physician-led approach looks beyond symptoms to identify the biological and metabolic factors contributing to weight gain